A case of verruciform xanthoma-light and electron microscopic observation

  • Takeshita Nobuyoshi
    Department of Oral Pathology, Iwate Medical University School of Dentistry
  • Satoh Masanobu
    Department of Oral Pathology, Iwate Medical University School of Dentistry
  • Suzuki Atsumi
    Department of Oral Pathology, Iwate Medical University School of Dentistry
  • Chiba Kiyoshi
    Department of Oral Surgery I, Iwate Medical University School of Dentistry
  • Tanifuji Masakatsu
    Department of Oral Surgery I, Iwate Medical University School of Dentistry
  • Kudoh Keigo
    Department of Oral Surgery I, Iwate Medical University School of Dentistry

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Other Title
  • Verruciform xanthomaの1症例
  • Verruciform xanthoma の1症例:とくに光顕的ならびに電顕的検討
  • 一とくに光顕的ならびに電顕的検討一

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Description

<p>A case of 47-year-old female with verruciform xanthoma in the region of the left lower first molar was reported. The clinical appearances of this lesion were similar to papilloma.</p><p>The light microscopical findings showed that the lesion was covered with stratified squamous epithelium and a verrucous or papillary architecture was noted in the epithelium. The depth of the epithelial rete pegs was rather uniform throughout the specimen. The outstanding characteristic of the specimen was the accumulation of foam cells with small rounded-oval nuclei between but not beneath the epithelial rete pegs. When the Sudan black B and the Sudan Ⅲ staining methods were used, the noticeable lipid droplets were demonstrated in the cytoplasms of these cells.</p><p>Electron microscopically, it was shown that lipid vacuoles varied in size and inclusion and, most of these vacuoles exhibited a smooth spherical contour and a electron lucency. The authers suspected that the lipid storing foam cells drived from histiocytes or macrophages.</p>

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