Squamous Cell Carcinoma Possibly Generated from Epidermal Cyst on the Face -Case Report and Summary of Japanese and Overseas Reports-

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  • Nagatani Kei
    Department of Dermatology, Yamagata University Faculty of Medicine
  • Hayashi Masahiro
    Department of Dermatology, Yamagata University Faculty of Medicine
  • Yaguchi Yoriko
    Department of Dermatology, Yamagata University Faculty of Medicine
  • Okamura Ken
    Department of Dermatology, Yamagata University Faculty of Medicine
  • Saito Toru
    Department of Dermatology, Yamagata University Faculty of Medicine
  • Tsunoda Takahiko
    Department of Dermatology, Yamagata City Hospital Saiseikan
  • Suzuki Tamio
    Department of Dermatology, Yamagata University Faculty of Medicine

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Other Title
  • 粉瘤から発生したと考えた顔面の有棘細胞癌―症例報告ならびに本邦報告例と海外報告例のまとめ―
  • フンリュウ カラ ハッセイ シタ ト カンガエタ ガンメン ノ ユウキョク サイボウ ガン : ショウレイ ホウコク ナラビニ ホンポウ ホウコクレイ ト カイガイ ホウコクレイ ノ マトメ

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Abstract

<p>The patient was a 65-year-old man who had a-few-year history of skin tumor on his left cheek. He was treated with antibiotics elsewhere with no response other than gradual enlargement. When he then visited our hospital, he presented with a 40 × 38 mm in diameter, pale red, multi-nodular subcutaneous mass; it had an ulcerative lesion in the center. Lymph nodes were swollen in his left neck. Ultrasonography showed a multilocular cyst structure. Skin biopsy taken from the tumor and positron emission tomography-computed tomography identified squamous cell carcinoma (SCC) with left cervical lymph node metastasis. After the complete resection and cervical lymphadenectomy, he was treated with radiotherapy in conjunction with systemic administration of S-1. Histologically, the cystic structure was obvious in the resected specimen, and the SCC was consecutive with the cyst wall. Although SCC rarely generates from epidermal cyst, patients with this condition often have atypical clinical manifestations. It is important to understand its characteristics for an accurate diagnosis.</p>

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