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- 立石 健祐
- 横浜市立大学大学院医学研究科脳神経外科学
Bibliographic Information
- Other Title
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- 特集 グリオーマ-現在の常識と近未来のスタンダード Ⅰ知っておくべきグリオーマの生物学的基礎知識 グリオーマの細胞生物学
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Description
In this review, I summarized the biology of gliomas. Through past clinical and basic studies, I reviewed the evidence of the cell of origin of gliomas and the presence of brain tumor-initiating cells in gliomas, which are driven by multiple genomic alterations. In addition, the complicated tumor heterogeneity and neuronal-glioma network were studied. These mechanisms may underlie the treatment resistance and poor prognosis and support the identification of novel therapeutic targets for gliomas.
Journal
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- Neurological Surgery 脳神経外科
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Neurological Surgery 脳神経外科 49 (3), 476-484, 2021-05-10
株式会社医学書院
