書誌事項
- タイトル別名
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- A Case of Pulmonary Nocardiosis Caused by <i>Nocardia otitidiscaviarum </i>in which the Causative Bacterium was Identified by MALDI-TOF MS
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<p>We report the case of an 88-year-old woman who was admitted with pneumonia. Sputum examination revealed aerobic actinomycetales, and we initiated the patient on therapy with imipenem/cilastatin (IPM/CS). However, the fever persisted, and the radiological findings started to worsen. On day 6 of the illness, N. otitidiscaviarum was identified by MALDI-TOF MS (Matrix As- sisted Laser Desorption Ionization Time of Flight Mass Spectrometry). We changed the antibacterial drug to ST, following which the patient improved. It has been reported that some bacterial species causing pulmonary nocardiosis show natural resistance to certain antibiotics. While not downplaying the significance of culture and drug sensitivity examinations, we suggest that for rare bacterial species, such as in the present case, the application of MALDI-TOF MS for identifying the bacterial species potentially allows early selection of effective therapeutic agents.</p>
収録刊行物
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- 感染症学雑誌
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感染症学雑誌 95 (1), 17-20, 2021-01-20
一般社団法人 日本感染症学会
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詳細情報 詳細情報について
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- CRID
- 1390851862123238784
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- NII論文ID
- 130008070696
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- ISSN
- 1884569X
- 03875911
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- CiNii Articles
- KAKEN
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- 使用不可