Symptom improvement for hypermenorrhea ; microwave endometrial ablation (MEA) vs levonorgestrel-releasing intrauterine system (LNG-IUS)

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  • 過多月経に対するマイクロ波子宮内膜焼灼治療とlevonorgestrel-releasing intrauterine system（LNG-IUS）治療の比較
  • カタ ゲッケイ ニ タイスル マイクロハ シキュウ ナイマク ショウシャク チリョウ ト levonorgestrel-releasing intrauterine system (LNG-IUS)チリョウ ノ ヒカク

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Abstract

<p>This study included 14 patients treated with microwave endometrial ablation (MEA) and 98 patients treated with first time insertion of a levonorgestrel-releasing intrauterine system (LNG-IUS).Questionnaires were completed at baseline and at one, three, and six months, as well as one, two, three, four and five years after treatment. The cases of LNG-IUS expulsion were identified from the medical records. According to the measures assessed in the questionnaires, hypermenorrhea and general fatigue were significantly improved compared with baseline in both groups. Menstrual duration improved after treatment in the MEA group. Volume-related symptoms were significantly improved in the LNG-IUS-treated group. Pain scores before the treatment tended to be higher in the LNG-IUS group than in the MEA group; however, the scores decreased rapidly after treatment in both groups. The frequency of LNG-IUS expulsions was about 18% in the first year and 23%, 27%, 29%, and 32%, respectively, from the second to the fifth years. The majority of cases of LNG-IUS expulsion were associated with the presence of uterine myomas or adenomyosis or both. MEA and LNG-IUS are minimally invasive treatments that may be effectively applied to reduce symptoms and improve quality of life of women with hypermenorrhea. [Adv Obstet Gynecol, 74 (3) : 301-308, 2022 (R4.8)]</p>

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