Safety evaluation of excessive intake of Proteoglycan Complex 80 from salmon nasal cartilage
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- Wada Tatsuya
- Nihon Pharmaceutical Co., Ltd.
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- Kobuna Yasuo
- Kobuna Orthopedic Clinic
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- Toida Toshihiko
- Center for Preventive Medical Sciences, Chiba University
Bibliographic Information
- Other Title
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- サケ鼻軟骨由来プロテオグリカン複合体80 の過剰摂取時における安全性の検討
- ―a randomized, double-blind, placebo-controlled, parallel-group study―
- ―プラセボ対照ランダム化二重盲検並行群間比較試験―
Abstract
Objective In the current study, we aimed to evaluate the safety of excessive intake of a dietary supplement containing Proteoglycan complex 80, derived from salmon nasal cartilage. <br>Methods This randomized, double-blind, placebo-controlled, parallel-group study enrolled 30 participants (39.5±9.7 years [mean±standard deviation]) who ingested a dietary supplement containing 200 mg of Proteoglycan complex 80 or placebo for four weeks. General blood and urine biomarkers for health and medical conditions were analyzed at 0, 2, 4, and 6 weeks. <br>Results There were no clinically relevant changes related to the test supplement. Furthermore, there were no side effects related to the intake of Proteoglycan complex 80. <br>Conclusion Our findings demonstrated the safety of excessive intake of the dietary supplement containing Proteoglycan complex 80 derived from salmon nasal cartilage.
Journal
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- Japanese Journal of Food Chemistry and Safety
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Japanese Journal of Food Chemistry and Safety 30 (3), 165-177, 2023-12-25
Japanese Society of Food Chemistry
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Details 詳細情報について
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- CRID
- 1390861538038782208
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- ISSN
- 21896445
- 13412094
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- Text Lang
- en
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed