Maternal Level of 25-Hydroxyvitamin D during Pregnancy Associated with Risk of Type 1 Diabetes in the Offspring, a Meta-Analysis
-
- KANG Xinyi
- Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nantong University (The First People’s Hospital of Nantong)
-
- CUI Jiawen
- Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nantong University (The First People’s Hospital of Nantong)
-
- ZHANG Mingjin
- Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nantong University (The First People’s Hospital of Nantong)
-
- WANG Ying
- Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nantong University (The First People’s Hospital of Nantong)
-
- TANG Weichun
- Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nantong University (The First People’s Hospital of Nantong)
-
- CHEN Liping
- Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nantong University (The First People’s Hospital of Nantong)
この論文をさがす
説明
<p>This aim of this meta-analysis was to evaluate the association between risk of childhood type 1 diabetes and maternal 25-hydroxyvitamin D [25(OH)D] levels during pregnancy. A literature search on databases including PubMed and Embase was conducted up to December 2018. The pooled odds radio weighted mean difference (WMD) and the corresponding 95% confidence intervals (CIs) were calculated using the RevMan 5.3 software. A total of 4 studies were included in this meta-analysis. The overall analysis indicated that the maternal 25(OH)D levels during pregnancy was significantly associated with the risk of type 1 diabetes in offspring (WMD=−2.54, 95% CI=−4.65 to −0.44, p=0.02). The subgroup analyses showed that sample for detection vitamin D (serum/plasma) may not a factor influencing the results of this meta-analysis. However, gestational trimester may be a factor affecting the results. The results showed that no significant association was observed between risk of type 1 diabetes in offspring and 25(OH)D level during first or second gestational trimester (p>0.05). Lower maternal 25(OH)D levels during pregnancy is associated with higher risk of type 1 diabetes in offspring. Gestational trimester may be a factor influencing the results of this meta-analysis.</p>
収録刊行物
-
- Journal of Nutritional Science and Vitaminology
-
Journal of Nutritional Science and Vitaminology 66 (5), 402-408, 2020-10-31
一般財団法人 学会誌刊行センター
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1391130851442601472
-
- NII論文ID
- 130007932353
-
- NII書誌ID
- AA00703822
-
- ISSN
- 18817742
- 03014800
-
- NDL書誌ID
- 030699239
-
- PubMed
- 33132342
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可