Recent Understanding of Eosinophilic Fasciitis

DOI Web Site

Bibliographic Information

Other Title
  • 好酸球性筋膜炎の最近の知見
  • コウサンキュウセイキンマクエン ノ サイキン ノ チケン

Search this article

Description

<p>　Eosinophilic fasciitis presents with wooden or plate-like hardening of the upper and lower extremities, but lacks either finger swelling or Raynaud’s phenomenon. Eosinophilic fasciitis is occasionally induced by vigorous exercise as well as trauma, leading to the hardening of the skin and limited range of movement in the joints. Also, drug-induced or paraneoplastic eosinophilic fasciitis have also been reported. An en block biopsy reveals an inflammatory infiltrate of mononuclear cells and eosinophils in the thickened fascia. Eosinophilic fasciitis is sometimes associated with several autoimmune conditions, and morphea is the most frequent skin disease. Recently, diagnostic criteria, severity classification, and clinical guidelines for eosinophilic fasciitis were proposed also in Japan. The etiology of eosinophilic fasciitis is still not fully elucidated, because this disorder is rare and animal models have not yet established. In this review, recent findings of eosinophilic fasciitis are described.</p><p>（日本皮膚免疫アレルギー学会雑誌, 3（2）：305-312, 2020）</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top