Mediastinal Neuroendocrine Carcinoma Slowly Growing for 8 Years after Surgical Resection of Esophageal Squamous Cell Carcinoma
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- Hirose Suguru
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Hasegawa Naoyuki
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Kawai Hitomi
- Department of Pathology, University of Tsukuba Hospital, Japan
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- Yamaura Masamichi
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Mizui Tsuneo
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Komatsu Yoshiki
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Nagase Masaomi
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Sato Masashi
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Hattori Junji
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Endo Masato
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Yamamoto Yoshiyuki
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Ishige Kazunori
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Fukuda Kuniaki
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Hyodo Ichinosuke
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan
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- Mizokami Yuji
- Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan Endoscopic Center, University of Tsukuba Hospital, Japan
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Abstract
<p>A 70-year-old woman was referred to our department due to a solitary mediastinal tumor which gradually grew near the site of anastomosis for 8 years after radical surgery of esophageal squamous cell carcinoma. It was difficult to distinguish the lymph node recurrence of esophageal cancer from another tumor of unknown primary origin. Endoscopic ultrasound-guided fine-needle aspiration was performed, and the tumor was diagnosed to be neuroendocrine carcinoma. She received concurrent chemoradiotherapy with etoposide plus cisplatin. After the completion of chemoradiotherapy, the tumor disappeared. A solitary growing tumor which develops after radical resection of cancer would be better to be examined histologically in order to make an accurate diagnosis and select the most appropriate treatment. </p>
Journal
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- Internal Medicine
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Internal Medicine 59 (20), 2505-2509, 2020-10-15
The Japanese Society of Internal Medicine