Nascent chain-mediated translation regulation in bacteria : translation arrest and intrinsic ribosome destabilization

書誌事項

タイトル別名
  • Multifaceted Protein World

この論文をさがす

抄録

<jats:title>Abstract</jats:title> <jats:p>Proteins that exsert physiological functions during being translated have been discovered from prokaryotes to eukaryotes. These proteins, also called regulatory nascent chains, are common in interacting co-translationally with the ribosomes to stall them. In most cases, such a translational arrest is induced or released in response to changes in the intracellular environment. Cells take advantage of such an environmental sensitivity as a sensor to feedback-regulate gene expression. Recent studies reveal that certain nascent chains could also destabilize the translating ribosomes, leading to stochastic premature translation termination. In this review, we introduce several examples of bacterial nascent chain-based mechanisms of translation regulation by which bacteria regulate cellular functions.</jats:p>

収録刊行物

参考文献 (79)*注記

もっと見る

関連プロジェクト

もっと見る

問題の指摘

ページトップへ