Recent Status of Group B Streptococcal (GBS) Infection of Newborn in Japan

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  • HOSHINA,Kiyoshi
    Department of Pediatrics, Tokyo Teishin Hospital
  • KADOI,Nobuaki
    Department of Pediatrics, Kitasato University School of Medicine
  • NISHIDA,Hiroshi
    Neonatal Division, Maternal and Perinatal Center Tokyo Women's Medical College
  • KANEKO,Kazuhiko
    Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital
  • MATSUDA,Seiji
    Department of Obstetrics and Gynecology, Kohtoh Hospital

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  • 新生児B群溶連菌(GBS)感染症の現状

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Group B streptococcal (GBS) infections in neonates have been a leading cause of bacterial infections. In many cases the infected neonates and young infants died or sequelae remained. The trend of cases, risk factors and prognosis of this disease have been the subjects of questionnaires for the past 5 years in Japan. The number of cases has increased year by year. Risk factors including amniotic turbidity, chorioamnionitis, premature rupture of membrane and fever during labor were recognized in 58% of early onset (less than 7 days of age) and in 28% of late onset (7 days and more of age) infant disease. Cases of death and remaining secluelae were 63(20.8%) of 303 early onset, 27(39.1%) of 69 late onset and 90(24.2%) out of a total of 372 cases. These results suggested that strategies for the prevention of GBS infections in the newborn are necessary.

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