4種の小型げっ歯類の脳心筋炎ウイルスに対する感受性
書誌事項
- タイトル別名
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- Susceptibility of Four Species of Small Rodents to Encephalomyocarditis (EMC) Virus Infection
抄録
The D variant of encephalomyocarditis virus (101-105 PFU/head) was intraperitoneally inoculated into 4 species of small rodents, rats, mice, Syrian hamsters, and Mongolian gerbils, and the susceptibillity of these animals to EMC virus was examined virologically and histopathologically 3 days after infection. Viral replication was detected in the brain (mice), in the heart (mice and gerbils), and in the pancreas (mice, hamsters, and gerbils) . No viral replication was detected in rats. Histopathological changes were seen in the brain (mice and hamsters), in the heart (mice and gerbils), and in the pancreas (mice, hamsters, and gerbils) . No histopathological changes were seen in rats. The present results suggest that it may be quite passible to produce EMC virus-induced diabetes mellitus not only in mice but also in hamsters and gerbils.
収録刊行物
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- Experimental Animals
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Experimental Animals 38 (4), 357-361, 1989
公益社団法人 日本実験動物学会
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詳細情報 詳細情報について
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- CRID
- 1571417127949607296
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- NII論文ID
- 130006940571
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- データソース種別
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- CiNii Articles