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Alpha 1-Antichymotrypsin and IgM as DNA-binding Protein in Serum : A Possible Diagnosis for Malignant Ovarian Tumors
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- OHKUBO Tomoichi
- Department of Biochemistry, School of Medicine, Tokai University
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- YAMAMURA Masaichi
- Department of Biochemistry, School of Medicine, Tokai University
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- KAMIGUCHI Hiroshi
- Division of Biochemistry, Interdepartmental Laboratory, School of Medicine, Tokai University
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- SAHASHI Tohru
- Department of Obstetrics and Gynecology, School of Medicine, Tokai Universtiy
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- HAYASHI Sigeoki
- Department of Obstetrics and Gynecology, School of Medicine, Tokai Universtiy
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- SHIOTSUKA Yukihiko
- Department of Obstetrics and Gynecology, School of Medicine, Tokai Universtiy
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- MATSUMOTO Masahiko
- Department of Biochemistry, School of Medicine, Tokai University
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- KOBAYASHI Kazuo
- Department of Obstetrics and Gynecology, School of Medicine, Tokai Universtiy
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- KATSUNUMA Tsunehiko
- Department of Biochemistry, School of Medicine, Tokai University
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Description
DNA-binding proteins were analysed in sera from patients with benign and malignant ovarian tumors by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Concentrations of proteins with molecular weights of 80,000 and 64,000 were selected to monitor malignancy since high levels in serum of patients were indicative of malignant disease. It was found that the value of the ratio between the DNA-binding proteins, alpha 1-antichymotrypsin and IgM, was a good index for diagnosing malignant ovarian tumors.
Journal
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- Tokai journal of experimental and clinical medicine
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Tokai journal of experimental and clinical medicine 7 (3), 325-329, 1982-05
Tokai University
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Details 詳細情報について
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- CRID
- 1571698601902185600
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- NII Article ID
- 110004690931
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- NII Book ID
- AA00863975
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- ISSN
- 03850005
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- Text Lang
- en
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- Data Source
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- CiNii Articles