Bioactive Saponins and Glycosides. IV. 1) Four Methyl-Migrated 16, 17-seco-Dammarane Triterpene Glycosides from Chinese Natural Medicine, Hoveniae Semen Seu Fructus, the Seeds and Fruit of Hovenia dulcis THUNB.: Absolute Stereostructures and Inhibitory Activity on Histamine Release of Hovenidulciosides A_1, A_2, B_1, and В_2
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- YOSHIKAWA Masayuki
- Kyoto Pharmaceutical University
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- MURAKAMI Toshiyuki
- Kyoto Pharmaceutical University
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- UEDA Tomohiko
- Kyoto Pharmaceutical University
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- MATSUDA Hisashi
- Kyoto Pharmaceutical University
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- YAMAHARA Johji
- Kyoto Pharmaceutical University
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- MURAKAMI Nobutoshi
- Kyoto Pharmaceutical University
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抄録
Four bioactive methyl-migrated 16,17-seco-dammarane type triterpene glycosides called hovenidulciosides A_1,A_2,B_1,and B_2 were isolated from a Chinese natural medicine, Hoveniae Semen seu Fructus, the seeds and fruit of Hovenia dulcis THUNB. (Rhamnaceae) together with hoduloside III and (+)-gallocatechin. The absolute stereostructures of hovenidulciosides A_1,A_2,B_1,and B_2 have been elucidated by chemical and physicochemical evidence. All were found to inhibit the histamine release from rat peritoneal exudate cells induced by compound 48/80 and calcium ionophore A-23187.
収録刊行物
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- Chemical & pharmaceutical bulletin
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Chemical & pharmaceutical bulletin 44 (9), 1736-1743, 1996-09-15
公益社団法人日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1571698602302057344
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- NII論文ID
- 110003632154
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- NII書誌ID
- AA00602100
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- ISSN
- 00092363
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- 本文言語コード
- en
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- データソース種別
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- CiNii Articles
