ISOLATION AND STRUCTURE OF REGELIN AND REGELINOL, NEW ANTITUMOR URSENE-TYPE TRITERPENOIDS FROM TRIPTERYGIUM REGELII(Communication to the Editor)

  • 堀 均
    Pharmaceutical Institute, School of Medicine, Keio University
  • 〓 国茂
    Pharmaceutical Institute, School of Medicine, Keio University
  • 播磨谷 健蔵
    Pharmaceutical Institute, School of Medicine, Keio University
  • 飯高 洋一
    Faculty of Pharmaceutical Sciences, The University of Tokyo
  • 稲山 誠一
    Pharmaceutical Institute, School of Medicine, Keio University

この論文をさがす

説明

Regelin (1a), a new antitumor ursene-type triterpenoid, the major principle, and another new ursene-type regelinol (1c) were isolated together with oleanene-type regelide (2) from the roots of Tripterygium regelii. The respective structures of 1a and 1c were determined, by ^1H-and ^<13>C-NMR spectrometric studies and X-ray analysis of 1a, to be the methyl ester of 3-oxo-22α-hydroxy-urs-12-en-30-oic acid and its 23-hydroxy analogue. 2 was found to be identical with wilforlide A or abruslactone A by comparing their physico-chemical data.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ