Ga-Labeling of Immunoglobulin G with High Specific Radioactivity

  • FURUKAWA Takako
    Department of Health Chemistry, Kansai Medical University
  • FUJIBAYASHI Yasuhisa
    Department of Radiopharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Kyoto University
  • FUKUNAGA Masao
    Division of Nuclear Medicine, Kawasaki Medical School
  • YOKOYAMA Akira
    Department of Radiopharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Kyoto University

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Description

To obtain radiogallium labeled immunoglobulin G with a high specific radioactivity for in vitro use, a ^<67>Ga source was purified by extraction from ^<67>Ga-gallium citrate with butyl acetate, and a ^<67>Ga-labeling solution was produced. This solution was then used to label a deferoxamine-immunoglobulin G conjugate. Both a very high specific radioactivity(872±56 MBq/mg) and a high labeling efficiency (94.0%) were achieved.

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Details 詳細情報について

  • CRID
    1574231877204503552
  • NII Article ID
    110003628765
  • NII Book ID
    AA00602100
  • ISSN
    00092363
  • Text Lang
    en
  • Data Source
    • CiNii Articles

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