Basic Fibroblast Growth Factor Fused with Tandem Collagen-Binding Domains from

Hiroyuki, Sekiguchi, Kentaro, Uchida, Osamu, Matsushita, Gen, Inoue, Nozomu, Nishi, Ryo, Masuda, Nana, Hamamoto, Takaki, Koide, Shintaro, Shoji, Masashi, Takaso

説明

Basic fibroblast growth factor 2 (bFGF) accelerates bone formation during fracture healing. Because the efficacy of bFGF decreases rapidly following its diffusion from fracture sites, however, repeated dosing is required to ensure a sustained therapeutic effect. We previously developed a fusion protein comprising bFGF, a polycystic kidney disease domain (PKD; s2b), and collagen-binding domain (CBD; s3) sourced from the

収録刊行物

BioMed research international

BioMed research international 2018 2017-12-01

キーワード

詳細情報詳細情報について

CRID: 1870865118108591744

ISSN: 23146141

PubMed: 29770338

データソース種別

OpenAIRE

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