Hedathiosulfonic acids A and B, novel thiosulfonic acids from the deep-sea urchin Echinocardium cordatum
書誌事項
- 公開日
- 2002-08-01
- DOI
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- 10.1016/s0040-4020(02)00654-3
- 10.1002/chin.200250208
- 公開者
- Elsevier BV
この論文をさがす
説明
Abstract Hedathiosulfonic acids A and B were isolated from the deep-sea urchin Echinocardium cordatum and were determined to be novel 6-undecanethiosulfonic acids by 2D NMR, HRMS, and methylation reaction. The stereostructure of hedathiosulfonic acid A was determined by the analysis of its degradation product, a cyclic β-hydroxysulfone. Hedathiosulfonic acids exhibited acute toxicity. We carried out various model reactions of the olefinic compounds with thiosulfonic acids and proved that, as is the case with natural products, synthesized thiosulfonic acid possessing a carbon–carbon double bond was converted into β-hydroxysulfone in the presence of oxygen.
収録刊行物
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- Tetrahedron
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Tetrahedron 58 6405-6412, 2002-08-01
Elsevier BV
