Inactivation of glutathione peroxidase by nitric oxide leads to the accumulation of H<sub>2</sub>O<sub>2</sub>and the induction of HB‐EGF via c‐Jun NH<sub>2</sub>‐terminal kinase in rat aortic smooth muscle cells
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- Young Ho Koh
- Department of BiochemistryOsaka University Medical School2–2 YamadaokaSuitaOsaka565–0871Japan
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- Keiichiro Suzuki
- Department of BiochemistryHyogo College of MedicineNishinomiyaHyogoJapan
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- Wenyi Che
- Department of BiochemistryOsaka University Medical School2–2 YamadaokaSuitaOsaka565–0871Japan
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- Yong Seek Park
- Department of BiochemistryOsaka University Medical School2–2 YamadaokaSuitaOsaka565–0871Japan
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- Yasuhide Miyamoto
- Department of BiochemistryOsaka University Medical School2–2 YamadaokaSuitaOsaka565–0871Japan
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- Shigeki Higashiyama
- Department of BiochemistryOsaka University Medical School2–2 YamadaokaSuitaOsaka565–0871Japan
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- Naoyuki Taniguchi
- Department of BiochemistryOsaka University Medical School2–2 YamadaokaSuitaOsaka565–0871Japan
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説明
SPECIFIC AIMSThis study addresses the hypothesis that nitric oxide (NO) up-regulates the heparin binding epidermal growth factor (EGF)-like growth factor (HB-EGF) through the accumulation of peroxi...
収録刊行物
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- The FASEB Journal
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The FASEB Journal 15 (8), 1472-1474, 2001-04-27
Wiley
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キーワード
- Glutathione Peroxidase
- Epidermal Growth Factor
- JNK Mitogen-Activated Protein Kinases
- Hydrogen Peroxide
- Nitric Oxide
- Models, Biological
- Gene Expression Regulation, Enzymologic
- Muscle, Smooth, Vascular
- Rats
- Animals
- Intercellular Signaling Peptides and Proteins
- fas Receptor
- Mitogen-Activated Protein Kinases
- Aorta
- Heparin-binding EGF-like Growth Factor
- Signal Transduction
詳細情報 詳細情報について
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- CRID
- 1360021396336959872
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- ISSN
- 15306860
- 08926638
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- PubMed
- 11387261
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- データソース種別
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- Crossref
- OpenAIRE