Liver Transplantation for Severe Alcoholic Hepatitis

DOI Web Site 37 References
  • Bekki Yuki
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
  • Yoshizumi Tomoharu
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • 重症アルコール性肝炎に対する肝移植の適応

Description

<p>Severe alcoholic hepatitis is a serious form of alcoholic liver disease, presenting as acute-on-chronic liver failure (ACLF). A national survey on ACLF in Japan revealed that 37.2% of the cases were because of severe alcoholic hepatitis, and the 1-month mortality of severe alcoholic hepatitis can reach to 30%-50% without liver transplantation (LT). Anecdotally, a certain period of abstinence is required for listing, although recent studies have demonstrated the effectiveness of early LT for severe alcoholic hepatitis with comparable alcoholic relapse post-LT. Multidisciplinary evaluation of social and psychological aspects and family support contribute to alcoholic relapse post-LT. Therefore, further studies may be warranted to identify the LT eligibility criteria for patients with severe alcoholic hepatitis.</p>

Journal

  • Kanzo

    Kanzo 65 (11), 533-540, 2024-11-01

    The Japan Society of Hepatology

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