The Indications for Liver Transplantation in Recipients with pre-transplant or Coexisting Malignancies

DOI
  • TOSHIMA Takeo
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
  • ITOH Shinji
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
  • YOSHIZUMI Tomoharu
    Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • 悪性腫瘍の既往・併存レシピエントに対する肝移植の適応

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Description

<p>The increase in liver transplant (LT) recipients’ age and improved survival rates have led to more patients with pre-transplant malignancies (PTMs). Common risk factors, like obesity and alcohol use, often link nonhepatic cancer with chronic liver diseases. Immunosuppressive therapy in LT recipients raises the risk of post-transplant cancer recurrence, affecting survival rates. Although PTM’s impact is well-studied in kidney transplants, data for LT is limited. Patients with cirrhosis and cancer have outcomes influenced by cirrhosis severity and chemotherapy’s impact on liver function. This study examines LT eligibility and required waiting period for PTM patients, focusing on cancer type and treatment history. Comprehensive cancer history is essential for evaluating LT eligibility. Future research should gather extensive data on PTM’s effect on post-LT outcomes, identifying recurrence risk factors to improve management and survival.</p>

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Details 詳細情報について

  • CRID
    1390583812015582592
  • DOI
    10.11386/jst.59.2_119
  • ISSN
    21880034
    05787947
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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