悪性腫瘍の既往・併存レシピエントに対する肝移植の適応
書誌事項
- タイトル別名
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- The Indications for Liver Transplantation in Recipients with pre-transplant or Coexisting Malignancies
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説明
<p>The increase in liver transplant (LT) recipients’ age and improved survival rates have led to more patients with pre-transplant malignancies (PTMs). Common risk factors, like obesity and alcohol use, often link nonhepatic cancer with chronic liver diseases. Immunosuppressive therapy in LT recipients raises the risk of post-transplant cancer recurrence, affecting survival rates. Although PTM’s impact is well-studied in kidney transplants, data for LT is limited. Patients with cirrhosis and cancer have outcomes influenced by cirrhosis severity and chemotherapy’s impact on liver function. This study examines LT eligibility and required waiting period for PTM patients, focusing on cancer type and treatment history. Comprehensive cancer history is essential for evaluating LT eligibility. Future research should gather extensive data on PTM’s effect on post-LT outcomes, identifying recurrence risk factors to improve management and survival.</p>
収録刊行物
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- 移植
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移植 59 (2), 119-128, 2024
一般社団法人 日本移植学会
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詳細情報 詳細情報について
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- CRID
- 1390583812015582592
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- ISSN
- 21880034
- 05787947
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可
